Upload Dna to 23 and Me for More Connections
23 and Me Review Summary
Summary
23 and Me offers one of the largest DNA databases at a competitive cost. Nonetheless, past privacy issues have been reported.
This review is written with the intent to be as unbiased as possible. However, it represents the opinion of an individual reviewer and is therefore subjective. Furthermore, at Nebula Genomics we seek to educate the public virtually the benefits of Whole Genome Sequencing. Data most our Whole Genome Sequencing DNA test is therefore incorporated into the review.
August 18, 2021
Table of Contents
- 7 Facts from our 23 and Me Review
- 23 and Me Introduction
- Review of 23 and Me Products and Services
- Review of 23 and Me Ancestry + Traits ($99)
- Review of 23 and Me Health + Ancestry ($199)
- Review of 23andMe + Membership ($29/year)
- Review of 23 and Me Privacy Policy
- 23 and Me in the News
- Other 23 and Me Reviews
- Nebula Genomics
- Your privacy is central
- Nebula Aggrandize
- Nebula Genomics 30x Whole-Genome Sequencing
7 Facts from our 23 and Me Review
- 23 and Me location: California, United states of america
- Products: DNA tests for ancestry and health
- Reports: detailed ancestry composition, power to notice relatives, diverse traits, carrier status, and genetic wellness risks
- Event delivery: 23 and Me results are delivered through a web portal and mobile app (iOS and Android)
- Privacy: active sharing of aggregate customer data with researchers
- 23 and Me price: $99-$499; no free Dna analysis options
- Alternatives: Nebula Genomics (Whole Genome Sequencing with advanced beginnings analysis and weekly updated reports)
23 and Me Introduction
This is a review of 23andMe (23 and Me, 23 & me), a genetic testing company is based out of Sunnyvale, California (Silicon Valley). The 23 and Me founder is Anne Wojcicki who started the company in 2006. The company was 1 of the first direct-to-consumer genetic testing services that emerged in the early 2000s, allowing individuals to access information about their genetics using rigorous standards without the involvement of medical professionals. After purchasing a home Dna exam, individuals provide saliva samples and they receive reports about their ancestry and genetic predispositions to specific traits and diseases. Over the years, the company has aggregated a lot of genetic data. To date, in that location are over 10 meg individuals in its database. Read more in our 23andMe review!
Review of 23 and Me Products and Services
Customers tin cull to order one of three 23 and Me DNA exam kits, ranging from $99 to $499. You can acquire more nigh how their prices compare to other companies on our blog. Customers tin can order a kit online from 23andMe.com. They can also buy products from major retailers such as Walgreens and Target. The collection kit includes instructions for how to provide a DNA sample to mail back to the company. Customers must register their 23andMe kit using their 23andMe login and apply that 23andMe sign in to access their results. One time customers receive their results, they can download raw data and use it with other analysis sites and marketplaces such as GenePlaza and sequencing.com.
How long does 23andMe take? Sample processing takes ii-3 weeks. Depending on which 23 and Me kit customers buy, different reports are included.
The visitor often runs popular 23andMe sales, including the almanac 23andMe Blackness Friday auction. These sales offering kits at up to fifty% up. 23andMe coupon codes on sites like Groupon also offer discounts.
Review of 23 and Me Ancestry + Traits ($99)
The basic 23andMe Ancestry + Traits Service includes eighty+ personalized reports for customers, including:
Beginnings Reports. 23andMe offers probably the all-time known for its ancestry testing. From their Ancestry Limerick Study, results show customers what proportion of their DNA comes from each of the 45 worldwide genetic populations (e.g. Ashkenazi jewish, African, Native American, etc.). Customers tin besides acquire about the ancient origin of their ancestors via Haplogroup Reports based on their mitochondrial DNA (for males and females) and Y chromosomes (just males). Moreover, the Neanderthal Beginnings Report allows customers to understand how much of their beginnings tin can be traced dorsum to Neanderthals through, an extinct species of hominids, through Neanderthal variants.
DNA Relatives Feature. The DNA relative finder is an optional characteristic, which allows customers to connect with genetic relatives on their family tree by identifying shared DNA segments. This enables the reconstruction of family history.
Traits Reports. Customers are able to explore how their genetics contributes to various traits they have, including reports on concrete features (due east.g. eye color, muscle composition), food preferences (e.thou. cilantro), and some traits that are mainly for fun (power to match musical pitch).
Review of 23 and Me Wellness + Ancestry ($199)
This part is a review of 23andMe health and ancestry DNA testing kit. The 23 and Me Wellness and Ancestry Service includes all features of the Ancestry + Traits, reporting plus additional 23andMe health reports:
Health Predispositions Reports. These are risk reports canonical by the Food and Drug Administration (FDA)* that help customers understand how genetics influences health outcomes, including breast and ovarian cancer and prostate cancer. Reports include health predispositions and carrier condition regarding increased hazard for developing diseases, including but not express to, increased chance of breast cancer and ovarian cancer, type 2 diabetes, Parkinson's illness, and celiac disease. Remember that increased cancer take chances or chance of other diseases does non necessarily mean that you lot will develop the weather condition.
Interested in genetic testing for hereditary cancer? You lot may be interested in these posts:
- Colon Cancer Genetic Testing
- Pancreatic Cancer Genetic Testing
- Genetic Testing for Breast Cancer
- Genetic Testing For Prostate Cancer
- Ovarian Cancer Genetic Testing
- Lung Cancer Genetic Testing
- Genetic Testing for Thyroid Cancer
Wellness Reports. This feature allows customers to understand how their genetics tin can influence lifestyle.
Carrier Condition Reports. These reports allow customers — that typically do non have a genetic health problems — empathize what genetic variants they may pass downwardly to their children that could affect their health. This report includes carrier condition of diseases such as sickle jail cell anemia.
*In 2013, 23 and Me received a warning letter of the alphabet from the FDA to stop marketing its testing kit, which provided health information without FDA blessing. With this in heed, the FDA issued guidance for companies producing direct-to-consumer tests. In 2015, 23 and Me launched a new service that met FDA requirements for being scientifically and clinically valid, and in 2017, the company was authorized to tell customers their genetic risk of developing sure medical conditions like Parkinson's' illness and Alzheimer's disease. According to the terms of service, 23 and Me results are for research, informational, and educational use merely and exercise not provide medical advice like professional person medical tests.
How authentic is 23andMe? Despite its human relationship with the FDA, 23andMe tests accept been criticized as not existence accurate enough for wellness care purposes.
Review of 23andMe + Membership ($29/year)
The 23andMe+ membership started on October i, 2020. With this membership, users get admission to 10+ exclusive genetic reports and new features as they become available.
Customers purchase their Wellness + Ancestry at a discounted toll of $169 with this membership for a total of $198.
Some of the exclusive reports and features available in this yearly programme are:
- Pharmacogenetic: Three reports to observe how your body processes certain medications.
- Hearth Health: Influence of genetics on your chances of developing sure heart-related conditions.
- Enhanced Ancestry: advanced features to those of the Beginnings written report, like access to 3,500 more than DNA relatives.
In general, this new service was not well received, particularly by current customers. They felt that these features should exist included in what they were already paying. Some clients agreed to participate in enquiry to help 23andMe proceeds new insights into weather condition. Hence, they felt that the results of this research they were function of were beingness locked behind a paywall.
Customer support had to come up up front end and explicate the 23andMe+ membership choice and why it was placed behind a paywall. The company still offers this plan, simply there are no reports on how successful information technology has been.
Sample Reports are bachelor on 23andMe's website:
- Ancestry Report: Ancestry Composition
- Traits Report: Bitter Taste
- Health Predisposition Written report: Celiac Illness
- Wellness Study: Genetic Weight
Carrier Condition Report: Cystic Fibrosis
Review of 23 and Me Privacy Policy
23 and Me secures customer data by stripping personal information, such as the customers' names and contact data, in the hope that "[the customer] cannot reasonably be identified as an individual." They also requite the customer the option of allowing 23 and Me to store their saliva sample afterward information technology has been analyzed.
What happens to the information 23andMe collects? 23 and Me states that it will not "sell, lease or hire [customer] individual-level information to whatsoever third party or to a third political party for research purposes without [the customer's] explicit consent." Still, the company does share aggregate information with third parties for other purposes, including research, business evolution, and sending marketing emails.
Customers can attain customer service at 1-800-239-5230.
23 and Me in the News
23andMe focuses on using genetic information for medical research and drug discovery. With the sizable genomic database that the visitor has congenital, information technology established its own therapeutics grouping in 2015 and built strategic partnerships with pharmaceutical companies.
However, there accept been some concerns about the privacy issues associated with 23anMe'southward partnership with pharmaceutical companies similar GlaxoSmithKline. Moreover, 23andMe sold the rights to a new drug for inflammatory diseases information technology developed using aggregate client data to the Castilian pharmaceutical company Almirall.
You can read more virtually data sharing and privacy concerns here: 23andMe is Terrifying, but Not for the Reasons the FDA Thinks.
In 2019, a journalist learns devastating health news from her 23andMe examination results and seeks advice from genetic counselors. They highlight the personal dangers that may come up with DNA testing, noting that they wished they had learned this health information from a person instead.
More recently, in April 2021, the visitor completed a merger with Richard Branson'southward VG Acquisition Corp. This merger helps make 23andMe more than simply a genetics visitor but a healthcare and drug discovery make, as pointed out by Anne Wojcicki, co-founder, and CEO. Last calendar month (July 2021), Marion Star, the local Marion news site, reported a woman who found a long-lost brother through 23andMe.
Other 23 and Me Reviews
23andMe reviews are available on multiple websites.
- 4.ane out of v stars for the Health + Beginnings service on their website with over 3600 reviews.
- 4.7 out of 5 stars on Amazon with over 26,000 reviews.
- ane.nine out of 5 stars on Trustpilot with 200 reviews. Nearly people that gave poor reviews signal that they never received a kit subsequently paying for the service.
- 3.7 out of 5 stars on consumeraffairs.com with 132 ratings.
Nebula Genomics
Nebula Genomics distinguishes itself from 23 and Me and other genetic testing companies through its focus on privacy, the utilise of most avant-garde testing technology, and the well-nigh comprehensive reporting. We cease our 23 and Me review by comparing it to Nebula Genomics and other Deoxyribonucleic acid testing companies.
Your privacy is fundamental
At Nebula Genomics, we believe that learning about how your genome encodes information most your health, personality, and ancestry can be invaluable, but we are likewise aware of the privacy risks. Therefore, at Nebula Genomics, we are edifice the showtime privacy-focused personal genomics service. Nosotros eliminate personal genetics companies every bit middlemen between data owners (i.e. customers) and data buyers (i.e. third parties), such that you can be compensated if you lot choose to share your data. Y'all can read more most the importance of Dna privacy on our website.
Nebula Expand
Yous can upload your DNA data from 23 and Me to find more nearly your genome with the Nebula Genomics expanded report. Nosotros create an expanded report by filling in the blanks of typical microarray-based DNA genotyping tests using statistical models, otherwise known as imputation. This expanded study gives you admission to hundreds of traits and curated inquiry studies through the Nebula Inquiry Library, allowing you lot to stay up-to-engagement with the most cutting-edge enquiry and what it means to yous and your Deoxyribonucleic acid.
Nebula Genomics 30x Whole-Genome Sequencing
Our goal is to empower our customers to take the pick to go beyond genetics tests that are offered by companies like 23 and Me and to unlock more information near themselves. With our 30x Whole-Genome Sequencing service, we determine 100% of your DNA. In other words, you volition go x,000 times more than data than with 23 and Me, which simply reads out 0.ane% of your genome! Here is how it compares with the 23 and Me or Ancestry genetic examination.
| | AncestryDNA | 23 and Me | Nebula Genomics |
| Dna Testing Method | Microarray-based genotyping | Microarray-based genotyping | Whole Genome Sequencing (30x coverage) |
| Data bachelor | Ancestry, wellness | Ancestry, traits, health | Weekly reports based on the latest inquiry, data exploration tools, deep ancestry (acquire more) |
| Able to upload raw DNA data | No | No | Aye (23 and Me and Ancestry) |
| Tools to explore data | Limited | Limited | Yes (acquire more) |
| Information access | Yes (Beginnings format file) | Yes (23 and Me format file) | Yes (FASTQ, BAM, and VCF files) |
| Cost | $99 – $119 | $99 – $199 | $0, $99, $299 |
Are you interested in other ancestry and genealogy services? Check out these reviews:
- 24Genetics (diverse tests for health, ancestry, sports, skin, pharmacogenomics, WES, and WGS)
- African Ancestry (various lineage examination for African descendants)
- AncestryDNA (ancestry, relative finder, and health)
- CRI Genetics (beginnings exam up to l generations)
- Deoxyribonucleic acid Consultants (specific ethnicities)
- DNA Land (free DNA upload for trait and beginnings analysis)
- Dna Painter (start profile is free and subscriptions are bachelor for others)
- Findmypast (genealogy for those with British and Irish ancestry)
- GedMatch Genesis (free DNA upload for genetic genealogy and paid advanced options)
- Genovate (relationship, health, fettle, and ancestry tests)
- HomeDNA Ancestry (migration history based on gene pools)
- iGenea (percentages origins, relatives, ancient tribes, and famous people)
- Living Dna (free upload for ancestry)
- MyHeritage (ancestry test, additional subscriptions for access to genealogy tools)
- TheGenealogist (UK based genealogy service)
- WeGene (Asian ancestry)
Many of these options likewise offer ancestry + traits or health test analysis for an additional price.
If you want to focus on your maternal and/or paternal lineages, y'all can look at YFull or YSeq, services which clarify mtDNA or the Y chromosome to determine specific lineage haplotypes. Full Genomes too offers Y chromosome sequencing and analysis.
Did you like our 23andMe review? You can read more reviews on our blog and check out our complete guide to the all-time DNA test kit and other home tests.
Source: https://nebula.org/blog/23-and-me-review/
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